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Step 4

Therapy continues while disease is under control and well tolerated

Continuation of therapy while disease is under control
The goal is for the treatment to keep the disease under control while maintaining a good quality of life. If scans and symptoms show improvement () or a stable condition, and side effects are acceptable, the treatment continues. When it becomes ineffective or too difficult to tolerate, the next is started.
When do we continue without change?

When the finding is better or stable (e.g., according to criteria), there are no new lesions, and side effects are mild/moderate.

How is treatment response assessed?

Symptoms, scans (usually a ), and the trend of are compared. means improvement, means the condition is not changing, and means worsening. How you feel and function in everyday life also matters.

Dose adjustment

If you have more pronounced , the doctor may reduce the dose or extend the interval between – so that the treatment remains tolerable and effective.

Supportive care

Treatment that helps you get through cancer therapy with as few side effects as possible, and thus maintain your quality of life.

Treatment breaks

Short breaks are sometimes possible (e.g., between or due to a procedure), but only in agreement with the medical team.

Safety first

If more severe occur (high fever, difficulty breathing, severe pain), the treatment may be temporarily paused, adjusted or even stopped if the symptoms are severe. That is why it is important to report any new symptom during treatment early, while it is still mild.

When is the treatment changed?

If scans show disease progression or side effects are too severe despite adjustments – the next is started.

Do small tumor marker fluctuations mean worsening?

Not necessarily. Trends over time are observed and compared with scans and symptoms. One measurement rarely changes the plan by itself.

Can I request a dose reduction?

Yes. If interfere with your daily life, tell the doctor – it is possible to reduce the dose or adjust the schedule without losing effectiveness.

How long can the same therapy last?

How long the same cancer treatment is given depends on the type of treatment – in general, it continues as long as it keeps the disease under control and is tolerable. Some drugs have a maximum cumulative dose that must not be exceeded (e.g., doxorubicin).

When to contact immediately?

  • Temperature over 38°C, chills (possible infection).
  • Difficulty breathing, chest pain, or severe new pain.
  • Persistent diarrhea.
  • Persistent vomiting, dehydration, confusion.
  • Pronounced rash, swelling of face/mouth (possible allergic reaction).

Balance between effectiveness and tolerability

In advanced disease, the goal is long-term control with a good quality of life. That is why the doctor takes into account scans, laboratory tests and your everyday functioning – all of this together guides the ‘continue / adjust / change’ decision.

Your role

  • Report all side effects – even mild ones, as they affect dose selection.
  • Keep a diary of symptom severity.
  • Ask for information about support: nutrition, exercise, psychologist, .